Drug Uses
Fosamax is indicated for treatment and prevention of osteoporosis in postmenopausal women. For the treatment of osteoporosis, Fosamax increases bone mass and reduces the incidence of fractures, including those of the hip and spine. It is also indicated for the prevention of osteoporosis, treatment to increase bone mass in men with osteoporosis, treatment of glucocorticoid. It is used to treat induced osteoporosis in men and women receiving glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and who have low bone mineral density, treatment of Paget's disease of bone in men and women.
How Taken
Fosamax comes as a tablet to take by mouth. It should be taken once a day in the morning on an empty stomach. Fosamax should be taken with a full glass (6-8 ounces) of plain water. Wait at least 30 minutes after taking Fosamax before you eat, drink, or take other medications. Do not take Fosamax with mineral water, coffee, orange juice, milk, or other dairy products. Do not suck or chew the tablet; swallow the tablet whole. Do not lie down for at least 30 minutes after taking Fosamax. Standing or sitting upright helps you get the full dose and decreases heartburn or the risk of injury to your esophagus.
Warnings/Precautions
Before taking Fosamax, tell your doctor if you have a problem swallowing, such as a narrowing of the esophagus; have esophageal ulcers or an esophageal disease; have a condition that causes low levels of calcium in the body; have kidney disease; have stomach ulcers or other stomach or digestive problems; or are unable to stand or sit upright for at least 30 minutes.
You may not be able to take Fosamax, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Fosamax is in the FDA pregnancy category C. This means that it is not known whether Fosamax will be harmful to an unborn baby. Do not take Fosamax without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether Fosamax passes into breast milk. Do not take Fosamax without first talking to your doctor if you are breast-feeding a baby.
Missed Dose
If you take Fosamax every day and you miss a dose, skip that dose and take the next regularly scheduled dose the following day. Missing one dose will not affect your treatment. Do not take two tablets at the same time.
If you take a Fosamax once a week and you miss a dose, take the missed dose on the morning after you remember. Do not take two tablets on the same day. Return to taking one tablet once a week, as originally scheduled on your chosen day.
Possible Side Effects
Stop taking Fosamax if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
Seek emergency or talk to your doctor if you have difficulty or pain when swallowing; chest pain; pain or burning under the ribs or in the back; or new or worsening heartburn.
Other, less serious side effects may be more likely to occur. Continue to take Fosamax and talk to your doctor if you experience abdominal discomfort; stomach upset, nausea, vomiting, diarrhea, or constipation; headache; muscle, bone, or joint soreness or aches; eye pain; a rash; or an altered sense of taste.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Store in a well-closed container at room temperature, 15-30°C (59-86°F).
Overdose
Hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, heartburn, esophagitis, gastritis, or ulcer, may result from oral over dosage. If you do think that an overdose has occurred, call an emergency room or poison control center.
More Information
Follow you doctor's recommendations about drinking alcohol and smoking. These activities are related to decreased bone density.
Antacids and other medicines taken by mouth may decrease the effects of Fosamax. Do not take any other medicines within 30 minutes after a dose of Fosamax. Talk to your doctor before taking any other medicines during treatment with Fosamax.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
For many years, consumers near Canada have driven across the border to buy their drugs at considerable savings from Canadian pharmacies. Now consumers across the country can purchase from Online-rxdrugstore.com.
Why Do People Use Online-rxdrugstore.com?
There are two leading reasons why people choose to obtain prescription drugs online. The first is cost. Due to the economics of health care in the United States, consumers often must pay a significantly higher price for medication than consumers in other countries. A second reason is privacy. Some people prefer to obtain Fosamax online, even at a higher cost, than to consult a doctor in person about issues such as depression, hair loss, or erectile dysfunction.
Q: Do you sell Fosamax?
A: Please review the section entitled products in your browser, a full list of medications are available there, some medications are considered controlled substances, the law requires that before these medicines can be dispensed that you undergo a physical exam, this means we cannot sell them online. Such medicines include Valium, Lorazepam, Ativan, Diazepam, Clonazepam, Klonopin and others.
Uterine Cancer
Also called: Endometrial cancer
The uterus, or womb, is an important female reproductive organ. It is the place where a baby grows when a women is pregnant. There are different types of uterine cancer. The most common type starts in the endometrium, the lining of the uterus. This type of cancer is sometimes called endometrial cancer.
The symptoms of uterine cancer include
* Unusual vaginal bleeding or discharge
* Trouble urinating
* Pelvic pain
* Pain during intercourse
Uterine cancer usually occurs after menopause. Being obese and taking estrogen-alone hormone replacement therapy also increase your risk. Treatment varies depending on your overall health, how advanced the cancer is and whether hormones affect its growth. Treatment is usually a hysterectomy, which is surgery to remove the uterus. Other options include hormone therapy and radiation.
About the Uterus and Endometrium
The uterus is a hollow organ, about the size and shape of a medium-sized pear. The uterus has two main parts. The lower end of the uterus, which extends into the vagina, is called the cervix. The upper part is the body of the uterus, also known as the corpus. (Corpus is the Latin word for body.) The body of the uterus has two layers. The inner layer is called the endometrium. (endo is Greek for inside and metrium is Greek for uterus.) The outer is called the myometrium. (myo is Greek for muscle.) The myometrium is the thick layer of muscle that pushes the baby out during birth.
Hormone changes during a woman?s menstrual cycle cause the endometrium to change. During the early part of the cycle, the ovaries (glands on either side of the uterus that produce eggs) produce estrogens. This causes the endometrium to thicken in order to nourish an embryo in case the woman becomes pregnant. After an ovary releases an egg (called ovulation), if pregnancy does not occur, estrogen is produced in lower amounts and more progesterone is made. This causes the innermost layer of the lining to prepare to shed. By the end of the cycle, the lining is shed from the uterus and becomes the menstrual flow. This cycle repeats throughout a woman?s life until menopause (change of life).
Cancers of the Uterus and Endometrium
Adenocarcinomas: Nearly all endometrial cancers (about 95%) are cancers of glandular cells, called adenocarcinomas. Most of these are described as typical adenocarcinomas.
Most experts divide endometrial adenocarcinomas into two types. In type 1, the cancer looks most like normal endometrium and may not be a very dangerous, life-threatening cancer. It only occasionally spreads to other tissues. This type is often called endometrioid, meaning it looks like normal endometrial lining tissue. There are three grades of tumor, with grade three being more aggressive with a greater risk of invasion to the uterine wall (myometrium), local and distant metastases.
Sometimes, in addition to glandular cells, endometrial cancers also contain squamous cells (the type of cells found on the surface of the cervix and the skin). If the squamous cells look benign (non-cancerous) under a microscope and the glandular cells look cancerous, these tumors are called adenocarcinomas with squamous differentiation (they used to be called adenoacanthomas, although this term is now used much less often). If the squamous areas and glandular areas both look malignant (cancerous), these tumors are called adenosquamous carcinomas. Although these look different under the microscope, they are treated the same as typical endometrial adenocarcinomas. However, adenosquamous carcinomas tend to be more aggressive.
Type 2 endometrial cancer doesn?t look at all like normal endometrium. It is much more likely to spread and is, therefore, more dangerous, These types are called either papillary serous adenocarcinomas or clear cell adenocarcinomas. About 10% of endometrial cancers are these types. Because they are different from the usual kind and tend to grow and spread they are treated more aggressively than the endometrioid cancers. Women with this type of cancer tend to be older by five to ten years on average, than women with type 1.
Uterine sarcomas: Uterine cancers that do not come from glandular tissue of the endometrium are called uterine sarcomas. They are less common, but can still involve other parts of the endometrium. These include:
* stromal sarcomas, which start in the stroma (supporting connective tissue) of the endometrium
* malignant mixed mesodermal tumors (MMMTs or carcinosarcomas), which may combine features of endometrial carcinoma and those of sarcomas
* leiomyosarcomas, which start in the myometrium or muscular wall of the uterus
These three types of cancer are not discussed in this document because their treatment and prognosis (the outlook for survival) are different from the most common cancers of the endometrium. These cancers are discussed in the document ?Uterine Sarcomas,? which is available from the American Cancer Society upon request or online.
Cervical cancers: Cancers of the cervix are different from cancers of the body of the uterus and are described in another American Cancer Society document.
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