Drug Uses

Famvir is an oral antiviral prescription medication that is prescribed for: treatment of recurrent genital herpes in otherwise healthy patients; suppression of recurrent genital herpes in otherwise healthy patients; treatment of recurrent herpes simplex virus infections (genital herpes and cold sores) in HIV-infected patients and herpes zoster (shingles).

How Taken

Famvir can be prescribed in one of three ways:
-Episodic treatment: your doctor treats an outbreak of genital herpes as it occurs. The usual dose of Famvir is one 125-mg pill, twice a day, for 5 days.
-Suppressive treatment: if you have frequent or severe outbreaks, you take one 250-mg pill, twice a day, for up to 1 year to suppress the genital herpes virus and help to prevent outbreaks.
-Patients with HIV: Famvir is the only prescription oral antiviral therapy indicated for treating genital. In patients with herpes simplex and HIV, the dose of Famvir is 500 mg, twice a day, for 7 days.
Famvir can be taken with or without food.

Warnings/Precautions

Do not take Famvir if you are allergic to penciclovir (Denavir) without first talking to your doctor. Before taking this medication, tell your doctor if you have kidney disease. You may need a dosage adjustment or special monitoring during treatment with Famvir. Famvir (Pregnancy Category B) should be used during pregnancy only if the benefit to the patient clearly exceeds the risk to the fetus.

Missed Dose

IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Possible Side Effects

Stop taking Famvir and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to take Famvir and talk to your doctor if you experience nausea or vomiting, a headache, diarrhea, dizziness, tingling in your hands or feet, or itching.

Storage

Store between 15C and 30C (59F and 86F) and out of reach of children.

Overdose

Seek emergency medical attention. A Famvir overdose has no known symptoms, but an overdose of acyclovir (Zovirax), which is a similar drug, may cause seizures, hallucinations, and kidney damage (decreased urine production).

More Information

Treatment with Famvir should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters). Take all of the Famvir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Herpes infections are contagious and you can infect other people, even during treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission. For more information, talk to your doctor, pharmacist or health care provider.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Genital herpes is a highly contagious viral condition caused by the herpes simplex virus (HSV). It principally infects the skin and mucous membranes of the genitals and rectum, but can also appear in areas such as the mouth. It is transmitted primarily through physical and sexual contact. During birth, the presence of herpes simplex virus on the genitalia or in the birth canal is a threat to the infant. Infection in the newborn infant can lead to herpetic meningitis, herpetic viremia (herpes virus particles present in the blood) and chronic skin infection
The symptoms of herpes simplex virus usually occur a week after infection, but sometimes take longer to appear. Initially, the skin becomes reddened and multiple small blisters filled with a clear, straw-coloured fluid appear. Prior to the presence of blisters, the infected individual may also experience increased skin sensitivity, tingling, burning or pain at the site where blisters will appear. Later, the blisters burst leaving shallow, painful ulcers which eventually scab and heal over a period of 7 to 14 days.
The outbreak may be accompanied by other symptoms such as:
# swelling and tenderness of the lymph nodes in the groin area.
# in women, vaginal discharge and painful urination.
# in men, a possibility of painful urination if the lesion is near the opening of the urethra.
# fever.
In most cases, a description of the condition and the appearance of the blisters will be enough to make a diagnosis. The GP may also advise referral to a specialist genitourinary medicine (GUM) clinic for confirmation of the diagnosis.
There is no cure for the herpes simplex virus; once infected, patients will remain a carrier for the rest of their lives. Some remedies, however, can reduce the duration of the eruption. In addition, by being more aware of the initial symptoms of recurrence (skin sensitivity and tingling), timely treatment with medication such as aciclovir (Zovirax tablets/suspension) will often abort the outbreak of blisters.
The best way to prevent recurrence is to avoid direct contact with an open lesion. People with herpes simplex virus should avoid sexual contact when active lesions are present.
Although the symptoms of genital herpes may not be present, it is important for those infected to inform their partner that they have the disease. This will encourage both parties to use barrier protection (condoms) to prevent the spread of the illness. Using condoms and not sharing towels are good ways of reducing the chance of infection in the first place.
For more information, read the factsheet on Herpes genitals.

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