Drug Uses

Celexa is in a class of drugs called selective serotonin reuptake inhibitors. Celexa affects chemicals in the brain that may become unbalanced and cause depression. Celexa is used to treat depression.

How Taken

Celexa comes as a tablet taken by mouth. It is usually taken once daily and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Celexa exactly as directed. Do not take more or less of it or take it more often that prescribed by your doctor. Continue to take Celexa even if you feel well. Do not stop taking Celexa without talking to your doctor. This drug must be taken regularly for a few weeks before its full effect is felt.

Warnings/Precautions

Before taking Celexa, tell your doctor if you have liver disease, have kidney disease, suffer from seizures, or suffer from mania or have suicidal thoughts. You may not be able to take Celexa, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Do not take Celexa without first talking to your doctor if you have had an allergic reaction to this medication in the past. Celexa is in the FDA pregnancy category C. This means that it is not known whether Celexa will be harmful to an unborn baby. Do not take Celexa without first talking to your doctor if you are pregnant or could become pregnant during treatment. Celexa passes into breast milk and may affect a nursing infant. Do not take Celexa without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

Possible Side Effects

The most common side effect with Celexa is sexual problems in male patients.
Some other possible side effects include:
-nausea
-dry mouth
-sleepiness
-increase in sweating

Storage

Celexa tablets should be stored in a dry place at room temperature between 15° and 30°C

Overdose

Symptoms most often accompanying Celexa overdose, alone or in combination with other drugs and/or alcohol, included dizziness, sweating, nausea, vomiting, tremor, somnolence, and sinus tachycardia. In more rare cases, observed symptoms included amnesia, confusion, coma, convulsions, hyperventilation, cyanosis, rhabdomyolysis, and ECG changes.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Celexa may cause dizziness. If you experience dizziness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Celexa or affect your condition.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Most of the Americans pay more for essential prescription medicines than the neighboring countries like Canada. And adding to this is the aggressive pricing policies of American pharmacy companies. The prices remain to continue to rise in the US, while they remain much less expensive in other countries. This disparity in prices has led to a rise in the popularity of Celexa.These discount pharmacies sell branded as well as exact generic equivalents of US FDA approved prescription drugs at a discounted rate, some even claiming to a saving of 70% off retail prices as they order in bulk.


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Thousands of people in the UK could be hooked on the anti-depressant drug Seroxat, without knowing it.
Dr David Healy, a UK expert in antidepressants, has said he has seen records of trials carried out by the manufacturers which showed healthy volunteers were suffering withdrawal symptoms after taking the drug for just a couple of weeks.
He said more than half of people on Seroxat may have "significant" withdrawal problems.
He said: "For most people who take the drug, one of the key points that will concern people is that Seroxat (paroxetine) could make you physically dependent."
Dr Healy, director of the North Wales department of psychological medicine was given access to the results of early trials of the drugs while a witness in a US case.
The case dealt with a seperate concern about the drug, which is that some people who take it could become violent towards themselves or others.
The family of David Snell won a $6.4m payout from manufacturers GlaxoSmithKline (GSK) after Mr Snell was found to have murdered three members of his family, and himself, after taking the drug for just two days.
The company denies the link and is appealing against the decision.
Two weeks earlier, in Australia, a judge ruled Sertraline, a drug in the same family, had caused David Hawkins to murder his wife and attempt to kill himself.
Dr Healy told BBC News Online, of the 100m people world-wide who were on Seroxat, one in 1,000 could have a suicidal reaction.
There have been concerns expressed in the past about antidepressants such as Prozac making healthy people with no history of mental illness feel violent.
New generation
Seroxat is part of a family of antidepressants called SSRIs (selective serotonin re-uptake inhibitor) which were introduced to the market in the early 1990s.
They were a replacement for benzodiazepines such as Valium and Librium - and their selling point was that people would not become physically dependent on them, unlike the older drugs.
Dr Healy was given access to GSK's archives because he was an expert witness in the Snell case.
And he said a trial a study of 34 healthy company workers by GSK, carried out before Seroxat was licensed, showed 25% became agitated.
Dr Healy believes a small number could be so disturbed by the effects of SSRIs that they could kill.
He said some of those involved in the pre-licensing trial had gone on to "suicidal acts".
He wrote to the Medicines Control Agency, which grants drug licenses in the UK, and said: "The relationship between their intake of paroxetine (Paxil/Seroxat) and later suicidal acts is a matter about which neither you, nor SmithKline Beecham should be sanguine."
Dr Healy said the company has failed to pass on information to patients or doctors.
He says a study which looked at the effect of stopping the drug for people who had successfully been treated for the depression showed many got worse.
The company argued this meant the drug should be licensed for long term treatment of depression.
Dr Healy says this is potentially more evidence that the participants in the trial were suffering withdrawal symptoms
He said the drug should carry warnings that some people who take it may experience violent or unusual thoughts, which were linked to the drug and not their condition.
And he said doctors who were treating people who suffered symptoms after coming off the drug "should be aware that maybe the underlying problem has cleared up and maybe the symptoms are due to withdrawal."
A World Health Organization report which ranked antidepressants in order of withdrawal problems found Seroxat was the hardest to come off.
Prozac (fluoxetine) was seventh.
Alan Chandler, a spokesman for GSK denied Seroxat was causing dependency, withdrawal symptoms or violent tendencies.
He said independent analysis last year by the MCA and others had concluded SSRIs did not cause dependency.
He said: "Withdrawal symptoms may occur with all SSRIs if treatment is abruptly stopped. This is not a sign of addiction or depression."

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